Enrolling 20% of All U.S. Patients for a Phase III Hypertension Trial with Narrow Inclusion Criteria

Context

In a Phase III trial targeting patients with CKD and hypertension, Panoramic Health is exceeding enrollment expectations despite representing only ~5% of participating sites. Narrow, complex eligibility criteria made recruitment challenging, yet the network significantly outperformed its target.

Objectives

Panoramic Health was selected to enroll patients for this study, which aims to assess the effectiveness of drug therapy in participants with CKD and high blood pressure.

National enrollment goal: 440 patients
Panoramic enrollment goal: 70 patients across 18 network sites
Target population: Adults age >18 with CKD and hypertension

Process

Panoramic Science streamlines enrollment through a data-driven funnel. EMR queries and chart reviews flag eligible patients, who are then referred by their treating nephrologist through a defined intake process. Central teams coordinate pre-screens, while rapid scheduling ensures patients move quickly from consent to enrollment.

Because research occurs in the patient’s own nephrology clinic with their trusted physician, participation does not cause undue burden on patients.

Impact

By enrolling 20% of all U.S. patients in the trial while representing just ~5% of sites, Panoramic Health demonstrates its ability to deliver outsized value and accelerate trial success.

patients enrolled across 18 Panoramic Health sites

above the enrollment target was exceeded

of the total U.S. enrollment for the entire trial was contributed, while only representing just ~5% of enrolling sites

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About Panoramic Health

Panoramic Health is kidney care’s leading integrated provider group, supporting a network of aligned nephrology practices across the U.S. treating hundreds of thousands of patients. Our mission is to slow disease progression and improve quality of life by empowering nephrologists with state-of-the-art clinical, operational, and financial solutions.

Founded by nephrologists, for nephrologists, Panoramic Health has a deep commitment to preserving clinical autonomy while supporting practice growth and reducing administrative burden. Our integrated model is built around the needs of complex kidney patients and enables partner practices to enhance care quality, reduce total cost of care, and access new revenue opportunities.